Well, considering I myself am involved in the same scenario, I'd have to go with the latter. Like any relationship, it depends on the people and effort they put in whether it will work or not, but species has no bearing on compatibility. It all depends on emotions, effort, and what both people are willing to put into it that counts.
Of course society does put added pressure on things, and I above others understand this considering my predicament, so I suppose in addition to all that you also must consider what you're willing to sacrifice to make it work. Basically, how badly do you want it?